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Exploring nanopore direct sequencing performance of forensic STRs, SNPs, InDels, and DNA methylation markers in a single assay.

Forensic science international. Genetics - 1 Jan 2025

de Bruin Desiree D S H, Haagmans Martin A, van der Gaag Kristiaan J, Hoogenboom Jerry, Weiler Natalie E C, Tesi Niccoló, Salazar Alex, Zhang Yaran, Holstege Henne, Reinders Marcel, M'charek Amade Aouatef, Sijen Titia, Henneman Peter

Abstract excerpt

INTRODUCTION: The field of forensic DNA analysis has undergone rapid advancements in recent decades. The integration of massively parallel sequencing (MPS) has notably expanded the forensic toolkit, moving beyond identity matching to predicting phenotypic traits and biogeographical ancestry. This shift is of particular significance in cases where conventional DNA profiling fails to identify a single suspect....

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PMID: 39426120
DOI: 10.1016/j.fsigen.2024.103154

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ELOVL2
FHL2

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