Article
Massively parallel sequencing of customised forensically informative SNP panels on the MiSeq.
Electrophoresis - 1 Oct 2016
Mehta Bhavik, Daniel Runa, Phillips Chris, Doyle Stephen, Elvidge Gareth, McNevin Dennis
Abstract excerpt
Forensic DNA-based intelligence, or forensic DNA phenotyping, utilises SNPs to infer the biogeographical ancestry and externally visible characteristics of the donor of evidential material. SNaPshot® is a commonly employed forensic SNP genotyping technique, which is limited to multiplexes of 30-40 SNPs in a single reaction and prone to PCR contamination. Massively parallel sequencing has the ability to genotype...
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