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Article

Mass cytometry identifies imbalance of multiple immune-cell subsets associated with biologics treatment in ankylosing spondylitis.

International journal of rheumatic diseases - 1 Oct 2024

Lin Li, Luo Jing, Cai Yue, Wu Xin, Zhou Ling, Li Ting, Wang Xiaobing, Xu Huji

Abstract excerpt

OBJECTIVE: This study aims to comprehensively investigate immune-cell landscapes in ankylosing spondylitis (AS) patients and explore longitudinal immunophenotyping changes induced by biological agents. METHODS: We employed mass cytometry with 35 cellular markers to analyze blood samples from 34 AS patients and 13 healthy controls (HC). Eleven AS patients were re-evaluated 1 month (4 patients) and 3 months (7...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39420773
DOI: 10.1111/1756-185X.15378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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