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Article

Genetic Analysis of Asymptomatic Antinuclear Antibody Production.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Mar 2025

Hocaoǧlu Mehmet, Casares-Marfil Desiré, Sawalha Amr H

Abstract excerpt

OBJECTIVE: Antinuclear antibodies (ANA) are detected in up to 14% of the population, and many individuals with ANA are asymptomatic. The literature on the genetic contribution to asymptomatic ANA positivity is limited. In this study, we aimed to perform a genome-wide association study of asymptomatic ANA positivity in multiple populations. METHODS: Asymptomatic individuals who were either ANA positive or ANA...

Read the complete abstract on PubMed

Topics

Humans
Antibodies, Antinuclear
Polymorphism, Single Nucleotide
Genome-Wide Association Study
Male
Female
Lupus Erythematosus, Systemic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Asymptomatic Diseases

Genetic Predisposition to Disease

Adult

HLA-DQ beta-Chains

Middle Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 39420706
DOI: 10.1002/art.43032
PMCID: PMC11865687

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