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Article

Monogenic and SLE-like disorders in the pediatric population: insights from a Northern Israel cohort.

Lupus - 1 Mar 2026

Spivak Ilia, Hershkovitz Tova, Weiss Karin, Zaid Rinat, Butbul Aviel Yonatan

Abstract excerpt

IntroductionWhile Systemic Lupus Erythematosus (SLE) typically presents with a multifactorial etiology, rare monogenic forms exist, usually diagnosed during childhood with a severe clinical course. This study aims to identify monogenic causes of SLE within the pediatric population of Northern Israel and to suggest criteria for genetic evaluation in patients with childhood-onset SLE.MethodsClinical and genetic...

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Source

Identifiers

PMID: 41530961
DOI: 10.1177/09612033261415976

Genes

C4B
ITPR3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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