Article
Demographic associations for autoantibodies in disease-free individuals of a European population.
Scientific reports - 28 Mar 2017
Haller-Kikkatalo Kadri, Alnek Kristi, Metspalu Andres, Mihailov Evelin, Metsküla Kaja, Kisand Kalle, Pisarev Heti, Salumets Andres, Uibo Raivo
Abstract excerpt
The presence of autoantibodies usually precedes autoimmune disease, but is sometimes considered an incidental finding with no clinical relevance. The prevalence of immune-mediated diseases was studied in a group of individuals from the Estonian Genome Project (n = 51,862), and 6 clinically significant autoantibodies were detected in a subgroup of 994 (auto)immune-mediated disease-free individuals. The overall...
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