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Article

Assessing inflammatory protein factors in inflammatory bowel Disease using multivariable mendelian randomization.

Scientific reports - 2 Jan 2025

Su Qiang, Lu Yun, He Song, Liang Jiang, Huang Song, He Yuanli, An Zhenxiang

Abstract excerpt

Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), decreases quality of life and causes disability. The underlying processes are not fully understood. This study uses Mendelian randomization (MR) analysis to identify cytokines that may be associated with UC and CD, aiding in early diagnosis and treatment decisions. Methods Genome-wide association study (GWAS) data for...

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Colitis, Ulcerative
Crohn Disease
Cytokines
Genetic Predisposition to Disease
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Inflammatory Bowel Diseases

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39747981
DOI: 10.1038/s41598-024-84447-4
PMCID: PMC11696058

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