Article
Unraveling the genetic and singaling landscapes of pediatric cancer.
Pathology, research and practice - 1 Nov 2024
Manjunath Gowrang Kasaba, Ankam Krishna Veni, Dakal Tikam Chand, Srihari Sharma M V, Nashier Disha, Mitra Tamoghna, Kumar Abhishek
Abstract excerpt
Pediatric cancer (PAEC) arises from gene mutations and their disrupted pathways, often driven by genetic instability affecting cell signaling. These pathways can help identify cancer triggers. Genomic studies have examined PAEC gene etiologies and disorders, but further analysis is needed to understand tumor progression mechanisms. We systematically analyzed PAEC datasets from cBioPortal, encompassing thirteen...
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