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Article

A Genome-Wide Association Study Reveals a Novel Susceptibility Locus for Pancreas Divisum at 3q29.

The Journal of surgical research - 1 Nov 2024

Gaitanidis Apostolos, Christensen Mathias A, Breen Kerry A, Kambadakone Avinash R, Joshipura Nencyben D, Fernandez-Del Castillo Carlos, Hernandez-Barco Yasmin G, Kaafarani Haytham M A, Velmahos George C, Farhat Maha R, Fagenholz Peter J

Abstract excerpt

INTRODUCTION: Pancreas divisum (PD) is a common congenital anomaly of the pancreas, but its genetic basis remains unknown. The purpose of this genome-wide association study was to identify genetic loci associated with PD. METHODS: Using the Mass General Brigham Biobank, patients diagnosed with PD were identified. Quality control and imputation were performed using standard approaches. Single nucleotide...

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PMID: 39393116
DOI: 10.1016/j.jss.2024.09.028

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MAF

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