Article
Common Variants in CLDN2 and MORC4 Genes Confer Disease Susceptibility in Patients with Chronic Pancreatitis.
PloS one - 1 Jan 2016
Giri Anil K, Midha Shallu, Banerjee Priyanka, Agrawal Ankita, Mehdi Syed Jafar, Dhingra Rajan, Kaur Ismeet, G Ramesh Kumar, Lakhotia Ritika, Ghosh Saurabh, Das Kshaunish, Mohindra Samir, Rana Surinder, Bhasin Deepak K, Garg Pramod K, Bharadwaj Dwaipayan
Abstract excerpt
A recent genome-wide association study (GWAS) identified association with variants in X-linked CLDN2 and MORC4, and PRSS1-PRSS2 loci with chronic pancreatitis (CP) in North American patients of European ancestry. We selected 9 variants from the reported GWAS and replicated the association with CP in Indian patients by genotyping 1807 unrelated Indians of Indo-European ethnicity, including 519 patients with CP and...
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