Article
Genome-wide Association Analysis for Organ Failure in Acute Pancreatitis.
Pancreas - 1 Apr 2026
Gaitanidis Apostolos, Christensen Mathias A, Albutt Katherine, Luckhurst Casey M, Fernandez-Del Castillo Carlos, Hernandez-Barco Yasmin, Velmahos George C, Fagenholz Peter J
Abstract excerpt
BACKGROUND: Patients with acute pancreatitis (AP) develop widely variable severity of organ failure. We hypothesized that genetic factors may influence the development of organ failure in AP. In this study, we identify candidate loci associated with organ failure in AP using genome-wide association analyses (GWAS) and transcriptomic analyses. METHODS: Subjects enrolled in the Mass General Brigham Biobank were...
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