Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic basis and causal relationship between atrial fibrillation and sinus node dysfunction: Evidence from comprehensive genetic analysis.

International journal of cardiology - 1 Jan 2025

Yan Zhaoqi, Pu Xiangyi, Chang Xing, Liu Zhiming, Liu Ruxiu

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) and sinus node dysfunction (SND) are commonly observed together clinically. However, little is known about the genetic background and causal relationship between the two. METHODS: Firstly, we investigated the global and local genetic correlations between AF and SND using LDSC and HESS. Then, we identified shared "Novel SNPs" between AF and SND through two complementary...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Fibrillation
Share to PITX2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Sick Sinus Syndrome

Source

Identifiers

PMID: 39389108
DOI: 10.1016/j.ijcard.2024.132609

Genes

BEST3
CEP68
ENPEP
PITX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic basis and causal relationship between atrial fibrillation and sinus node dysfunction: Evidence from comprehensive genetic analysis.PMID 39389108Read ↗

Genome-wide association study of 1 million people identifies 111 loci for atrial fibrillationSemantic proximity Read ↗

Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility.Semantic proximity Read ↗

Genetics of atrial fibrillation-an update of recent findings.Semantic proximity Read ↗

Deciphering the genetic architecture of atrial fibrillation offers insights into disease prediction, pathophysiology and downstream sequelaeSemantic proximity Read ↗

Atrial fibrillation: the role of common and rare genetic variants.Semantic proximity Read ↗

Novel Genes Associated With Atrial Fibrillation and the Predictive Models for AF Incorporating Polygenic Risk Score and PheWAS-Derived Risk Factors.Semantic proximity Read ↗

A Network and Pathway Analysis of Genes Associated With Atrial Fibrillation.Semantic proximity Read ↗

An integrated genome and phenome-wide association study approach to understanding atrial fibrillation’s disease predispositionSemantic proximity Read ↗

Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.Semantic proximity Read ↗

Multiomics Analysis of Genetics and Epigenetics Reveals Pathogenesis and Therapeutic Targets for Atrial Fibrillation.Semantic proximity Read ↗

Genome-Wide Association Study of Accessory Atrioventricular Pathways.Semantic proximity Read ↗

Genomics of Atrial Fibrillation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.