Article
Genetic analyses of 104 phenotypes in 20,900 Chinese pregnant women reveal pregnancy-specific discoveries.
Cell genomics - 9 Oct 2024
Xiao Han, Li Linxuan, Yang Meng, Zhang Xinyi, Zhou Jieqiong, Zeng Jingyu, Zhou Yan, Lan Xianmei, Liu Jiuying, Lin Ying, Zhong Yuanyuan, Zhang Xiaoqian, Wang Lin, Cao Zhongqiang, Liu Panhong, Mei Hong, Cai Mingzhi, Cai Xiaonan, Tao Ye, Zhu Yunqing, Yu Canqing, Hu Liqin, Wang Yu, Huang Yushan, Su Fengxia, Gao Ya, Zhou Rui, Xu Xun, Yang Huanming, Wang Jian, Zhu Huanhuan, Zhou Aifen, Jin Xin
Abstract excerpt
Monitoring biochemical phenotypes during pregnancy is vital for maternal and fetal health, allowing early detection and management of pregnancy-related conditions to ensure safety for both. Here, we conducted a genetic analysis of 104 pregnancy phenotypes in 20,900 Chinese women. The genome-wide association study (GWAS) identified a total of 410 trait-locus associations, with 71.71% reported previously. Among the...
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