Article
Genome-wide association studies of thyroid-related hormones, dysfunction, and autoimmunity among 85,421 Chinese pregnancies.
Nature communications - 13 Sept 2024
Wei Yuandan, Zhen Jianxin, Hu Liang, Gu Yuqin, Liu Yanhong, Guo Xinxin, Yang Zijing, Zheng Hao, Cheng Shiyao, Wei Fengxiang, Xiong Likuan, Liu Siyang
Abstract excerpt
Maintaining normal thyroid function is crucial in pregnancy, yet thyroid dysfunction and the presence of thyroid peroxidase antibodies (TPOAb) affect 0.5% to 18% of pregnant women. Here, we conducted a genome-wide association study (GWAS) of eight thyroid traits, including two thyroid-related hormones, four thyroid dysfunctions, and two thyroid autoimmunity measurements among 85,421 Chinese pregnant women to...
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