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Article

Genetics of hand grip strength in mid to late life.

Age (Dordrecht, Netherlands) - 1 Feb 2015

Chan Jessica P L, Thalamuthu Anbupalam, Oldmeadow Christopher, Armstrong Nicola J, Holliday Elizabeth G, McEvoy Mark, Kwok John B, Assareh Amelia A, Peel Rosanne, Hancock Stephen J, Reppermund Simone, Menant Jasmine, Trollor Julian N, Brodaty Henry, Schofield Peter R, Attia John R, Sachdev Perminder S, Scott Rodney J, Mather Karen A

Abstract excerpt

Hand grip strength (GS) is a predictor of mortality in older adults and is moderately to highly heritable, but no genetic variants have been consistently identified. We aimed to identify single nucleotide polymorphisms (SNPs) associated with GS in middle-aged to older adults using a genome-wide association study (GWAS). GS was measured using handheld dynamometry in community-dwelling men and women aged 55-85 from...

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PMID: 25637336
DOI: 10.1007/s11357-015-9745-5
PMCID: PMC4312310

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