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Article

RfaH contributes to maximal colonization and full virulence of hypervirulent Klebsiella pneumoniae

17 Sept 2024

Abstract excerpt

Hypervirulent K. pneumoniae (hvKp) have emerged as clinically important pathogens, posing a serious threat to human health. RfaH, a transcriptional elongation factor, has been regarded as implicated in facilitating the transcription of long virulence operons in certain bacterial species. In K. pneumoniae, RfaH plays a vital role in promoting CPS synthesis and hypermucoviscosity, as well as mediating bacterial...

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PMID: 39364146
DOI: 10.3389/fcimb.2024.1454373

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