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Article

Adaptive attenuation of virulence in hypervirulent carbapenem-resistant Klebsiella pneumoniae.

mSystems - 18 Jun 2024

Teng Gaoqin, Zhang Meng, Fu YingYing, Yang Xiaoqiang, Kang Yanhua, Qin Qiuying, Jin Ye, Huang Man, Xu Yongchang

Abstract excerpt

The emergence of nosocomial infections caused by hypervirulent and carbapenem-resistant K. pneumoniae (hv-CRKP) has become a significant public health challenge. The genetic traits of virulence and resistance plasmids in hv-CRKP have been extensively studied; however, research on the adaptive evolution strategies of clinical strains inside the host was scarce. This study aimed to understand the effects of...

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Identifiers

PMID: 38752758
DOI: 10.1128/msystems.01363-23
PMCID: PMC11237801

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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