Article
The KbvR Regulator Contributes to Capsule Production, Outer Membrane Protein Biosynthesis, Antiphagocytosis, and Virulence in Klebsiella pneumoniae.
Infection and immunity - 16 Apr 2021
Xu Li, Wang Meng, Yuan Jie, Wang Hui, Li Moran, Zhang Fusheng, Tian Yujiao, Yang Jing, Wang Jingjie, Li Bei
Abstract excerpt
Klebsiella pneumoniae is an opportunistic pathogen that mostly affects patients with weakened immune systems, but a few serotypes (especially K1 and K2) are highly invasive and result in systemic infection in healthy persons. The ability to evade and survive the components of the innate immune system is critical in infection. To investigate the role and mechanism of transcription regulator KP1_RS12260 (KbvR) in...
Topics
- Animals
- Bacterial Capsules
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Gene Expression Regulation, Bacterial
- Host-Pathogen Interactions
- Humans
- Immunity, Innate
- Klebsiella Infections
- Klebsiella pneumoniae