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Article

Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors

2 Oct 2024

Abstract excerpt

White adipose tissue (WAT) is essential for lipid storage and systemic energy homeostasis. Understanding adipocyte formation and stability is key to developing therapies for obesity and metabolic disorders. Through a high-throughput cDNA screen, we identified PATZ1, a POZ/BTB and AT-Hook Containing Zinc Finger 1 protein, as an important adipogenic transcription factor. PATZ1 is expressed in human and mouse...

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PMID: 39358382
DOI: 10.1038/s41467-024-52917-y

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