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Article

Single-cell transcriptional networks in differentiating preadipocytes suggest drivers associated with tissue heterogeneity.

Nature communications - 30 Apr 2020

Ramirez Alfred K, Dankel Simon N, Rastegarpanah Bashir, Cai Weikang, Xue Ruidan, Crovella Mark, Tseng Yu-Hua, Kahn C Ronald, Kasif Simon

Abstract excerpt

White adipose tissue plays an important role in physiological homeostasis and metabolic disease. Different fat depots have distinct metabolic and inflammatory profiles and are differentially associated with disease risk. It is unclear whether these differences are intrinsic to the pre-differentiated stage. Using single-cell RNA sequencing, a unique network methodology and a data integration technique, we predict...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32355218
DOI: 10.1038/s41467-020-16019-9
PMCID: PMC7192917

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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