Article
CARD8 polymorphisms among bacterial meningitis patients in North-West Ethiopia.
BMC infectious diseases - 1 Oct 2024
Belayneh Meseret, Mengesha Mesfin, Idosa Berhane A, Fentaw Surafel, Moges Biniyam, Tazu Zelalem, Assefa Meseret, Garpenholt Örjan, Persson Alexander, Särndahl Eva, Abate Ebba, Säll Olof, Gelaw Baye
Abstract excerpt
BACKGROUND: The severity of infectious disease outcomes is dependent on the virulence factors of the pathogen and the host immune response. CARD8 is a major regulator of the innate immune proinflammatory response and has been suggested to modulate the host response to common inflammatory diseases. In the present study, the C10X genetic polymorphism in the CARD8 gene was investigated in relation to bacterial...
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