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Article

Causal relationships between epilepsy and the microstructure of the white matter: A Mendelian randomization study.

Medicine - 1 Nov 2024

Xie Zhijun, Chen Zhe, Jiang Yuhong, Yao Jiaqi, Zhang Pengcheng, Lei Hang, Tang Wenfu

Abstract excerpt

To examine the causal bidirectional relationships between epilepsy and microstructural changes in the white matter (WM). A genome-wide association study meta-analysis of the International League Against Epilepsy Consortium on Epilepsy and 360 WM imaging-derived phenotypes (IDPs) from the UK Biobank was used for the analysis. Genetic correlation analyses were conducted based on summary statistics of various...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39496061
DOI: 10.1097/MD.0000000000040090
PMCID: PMC11537589

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