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Article

A pioneering study indicate role of GABRQ rs3810651 in ASD severity of Indo-Caucasoid female probands.

Scientific reports - 26 Mar 2021

Saha Sharmistha, Chatterjee Mahasweta, Sinha Swagata, Mukhopadhyay Kanchan

Abstract excerpt

Alteration in gamma aminobutyric acid (GABA), the principal inhibitory neurotransmitter, is speculated to be a potential risk factor for Autism Spectrum Disorder (ASD) due to an altered expression in the brain. Sensory, social, and emotional deficits of subjects with ASD were reported to be caused by an imbalance between excitatory and inhibitory neurotransmission as well as GABAergic dysfunction caused by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33772085
DOI: 10.1038/s41598-021-86496-5
PMCID: PMC7997895

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