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Article

Cold Exposure Rejuvenates the Metabolic Phenotype of Panx1-/- Mice.

Biomolecules - 25 Aug 2024

Molica Filippo, Ehrlich Avigail, Pelli Graziano, Rusiecka Olga M, Montessuit Christophe, Chanson Marc, Kwak Brenda R

Abstract excerpt

Pannexin1 (Panx1) ATP channels are important in adipocyte biology, potentially influencing energy storage and expenditure. We compared the metabolic phenotype of young (14 weeks old) and mature (20 weeks old) wild-type (WT) and Panx1-/- mice exposed or not to cold (6 °C) during 28 days, a condition promoting adipocyte browning. Young Panx1-/- mice weighed less and exhibited increased fat mass, improved glucose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39334824
DOI: 10.3390/biom14091058
PMCID: PMC11430693

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