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Article

γ-Aminobutyric acid type A receptor β1 subunit gene polymorphisms are associated with the sedative and amnesic effects of midazolam.

Molecular brain - 27 Sept 2024

Kosaki Yoshihiko, Nishizawa Daisuke, Hasegawa Junko, Yoshida Kaori, Ikeda Kazutaka, Ichinohe Tatsuya

Abstract excerpt

Midazolam is widely used for intravenous sedation. However, wide interindividual variability is seen in the sensitivity to midazolam. The association between genetic factors and interindividual differences in midazolam sensitivity remains unclear. The present study explored the association between common genetic variants and sedative and amnesic effects of midazolam. This prospective study included patients who...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39334212
DOI: 10.1186/s13041-024-01141-2
PMCID: PMC11428381

Genes

GABRB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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