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Article

Gamma-aminobutyric acid (GABA) receptors GABRA4, GABRE, and GABRQ gene polymorphisms and risk for migraine.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2018

García-Martín Elena, Esguevillas Gara, Serrador Mercedes, Alonso-Navarro Hortensia, Navacerrada Francisco, Amo Gemma, García-Albea Esteban, Agúndez José A G, Jiménez-Jiménez Félix Javier

Abstract excerpt

Several biochemical, pharmacological, neurophysiological and experimental data suggest a possible role of gamma-aminobutyric acid (GABA) in the pathogenesis of migraine. We investigated the possible association of the most common single nucleotide polymorphisms (SNPs) in the GABA receptor alpha4 (GABRA4), epsilon (GABRE), and theta (GABRQ) genes with the risk for migraine. A TaqMan-based qPCR assay designed to...

Topics

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Age of Onset
Genetic Predisposition to Disease
Genotype
Migraine Disorders
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, GABA-A

Source

Identifiers

PMID: 29299688
DOI: 10.1007/s00702-017-1834-4

Genes

GABRQ
GABRA4
GABRE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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