Article
Molecular genetic analysis of colorectal carcinoma with an aggressive extraintestinal immunohistochemical phenotype.
Scientific reports - 27 Sept 2024
Hrudka Jan, Kalinová Markéta, Fišerová Hana, Jelínková Karolína, Nikov Andrej, Waldauf Petr, Matěj Radoslav
Abstract excerpt
Colorectal cancer (CRC) is a leading global cause of illness and death. There is a need for identification of better prognostic markers beyond traditional clinical variables like grade and stage. Previous research revealed that abnormal expression of cytokeratin 7 (CK7) and loss of the intestinal-specific Special AT-rich sequence-binding protein 2 (SATB2) are linked to poor CRC prognosis. This study aimed to...
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