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Progress in clinical diagnosis and treatment of colorectal cancer with rare genetic variants.

Cancer biology & medicine - 15 Jun 2024

Chen Shuyi, Gu Jing, Wu Kaichun, Zhao Xiaodi, Lu Yuanyuan

Abstract excerpt

Targeted therapy is crucial for advanced colorectal cancer (CRC) positive for genetic drivers. With advances in deep sequencing technology and new targeted drugs, existing standard molecular pathological detection systems and therapeutic strategies can no longer meet the requirements for careful management of patients with advanced CRC. Thus, rare genetic variations require diagnosis and targeted therapy in...

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PMID: 38940668
DOI: 10.20892/j.issn.2095-3941.2024.0026
PMCID: PMC11208903

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