Article
Reduced Platelet Activation in Triple-Negative Essential Thrombocythemia Compared with JAK2V617F-Mutated Essential Thrombocythemia.
Clinical cancer research : an official journal of the American Association for Cancer Research - 2 Dec 2024
Dong Huan, Chen Jia, Zhang Jing, Xue Feng, Li Huiyuan, Zhang Donglei, Zhou Hu, Zhang Xian, Huang Yueting, Liu Xiaofan, Chen Yunfei, Liu Wei, Chi Ying, Wang Wentian, Sun Ting, Ju Mankai, Dai Xinyue, Gu Wenjing, Yang Renchi, Fu Rongfeng, Zhang Lei
Abstract excerpt
PURPOSE: Triple-negative (TN) essential thrombocytopenia (ET) is characterized by the absence of driver mutations while retaining histologic and phenotypic characteristics sufficient for an ET diagnosis. Our understanding of TN-ET and its platelet activation remains incomplete. We carried out a large-scale multicenter clinical analysis to analyze the clinical and molecular characteristics and thrombotic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.