Polymorphisms of CD44 rs187115 as a Predictive Biomarker in Early Colorectal Cancer Diagnostic.

doi:10.21614/chirurgia.3007

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Article

Polymorphisms of CD44 rs187115 as a Predictive Biomarker in Early Colorectal Cancer Diagnostic.

Chirurgia (Bucharest, Romania : 1990) - 1 Sept 2024

Dumache Raluca, Mihailescu Alexandra, David Dana Liana, Herlo Flavius-Lucian, Verdeş Gabriel, Brebu Dan, Faur Ionuţ, Braicu Vlad, Dobrescu Amadeus, Duţă Ciprian

Abstract excerpt

Introduction: Colorectal cancer (CRC) has exhibited an increasing incidence worldwide in recent years, underscoring the importance of early diagnosis methods. This study aimed to assess the influence of CD44 gene polymorphism rs187115 on CRC susceptibility. Material and Methods: The study encompassed 470 CRC patients and 165 healthy controls. Genotyping of all biological blood samples was conducted using the...

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PMID: 39312645
DOI: 10.21614/chirurgia.3007

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