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Article

Distinct Responses of Cystic Fibrosis Epithelial Cells to SARS-CoV-2 and Influenza A Virus.

American journal of respiratory cell and molecular biology - 1 Mar 2025

Pagani Isabel, Venturini Arianna, Capurro Valeria, Nonis Alessandro, Ghezzi Silvia, Lena Mariateresa, Alcalá-Franco Beatriz, Gianferro Fabrizio, Guidone Daniela, Colombo Carla, Pedemonte Nicoletta, Bragonzi Alessandra, Cigana Cristina, Galietta Luis J V, Vicenzi Elisa

Abstract excerpt

The coronavirus disease (COVID-19) pandemic has underscored the impact of viral infections on individuals with cystic fibrosis (CF). Initial observations suggested lower COVID-19 rates among CF populations; however, subsequent clinical data have presented a more complex scenario. This study aimed to investigate how bronchial epithelial cells from individuals with and without CF, including various CFTR (CF...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39311876
DOI: 10.1165/rcmb.2024-0213OC
PMCID: PMC11890075

Genes

CFTR
ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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