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Article

Effects of cystic fibrosis transmembrane conductance regulator and DeltaF508CFTR on inflammatory response, ER stress, and Ca2+ of airway epithelia.

American journal of physiology. Lung cellular and molecular physiology - 1 Nov 2007

Hybiske Kevin, Fu Zhu, Schwarzer Christian, Tseng Jill, Do Jiun, Huang Natalie, Machen Terry E

Abstract excerpt

We tested whether cystic fibrosis (CF) airway epithelia have larger innate immune responses than non-CF or cystic fibrosis transmembrane conductance regulator (CFTR)-corrected cells, perhaps resulting from ER stress due to retention of DeltaF508CFTR in the endoplasmic reticulum (ER) and activatio...

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Source

Identifiers

PMID: 17827250
DOI: 10.1152/ajplung.00231.2007

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17827250-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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