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Article

Genome-wide association study between SARS-CoV-2 single nucleotide polymorphisms and virus copies during infections.

PLoS computational biology - 1 Sept 2024

Li Ke, Chaguza Chrispin, Stamp Julian, Chew Yi Ting, Chen Nicholas F G, Ferguson David, Pandya Sameer, Kerantzas Nick, Schulz Wade, Hahn Anne M, Ogbunugafor C Brandon, Pitzer Virginia E, Crawford Lorin, Weinberger Daniel M, Grubaugh Nathan D

Abstract excerpt

Significant variations have been observed in viral copies generated during SARS-CoV-2 infections. However, the factors that impact viral copies and infection dynamics are not fully understood, and may be inherently dependent upon different viral and host factors. Here, we conducted virus whole genome sequencing and measured viral copies using RT-qPCR from 9,902 SARS-CoV-2 infections over a 2-year period to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39288189
DOI: 10.1371/journal.pcbi.1012469
PMCID: PMC11432881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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