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Article

Agreement between Phenotypically Detected Linezolid Resistance and Mutations in rrl and rplC Genes of Mycobacterium tuberculosis Isolates Using Nanopore Sequencing.

International journal of mycobacteriology - 1 Jul 2024

Sengupta Senjuti, Jain Parul, Ratnam Rashmi, Pandey Bhoopendra Kumar, Singh Urmila, Kumar Vijay, Paliwal Ashutosh, Jain Amita

Abstract excerpt

BACKGROUND: Phenotypic drug susceptibility testing (DST) is considered the gold standard for detecting linezolid (LZD) resistance in Mycobacterium tuberculosis (MTB), but it is time-consuming. Nanopore sequencing offers a potentially faster alternative approach. This study evaluated the agreement between phenotypically detected LZD resistance and mutations in the rrl and rplC genes of MTB isolates using nanopore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39277897
DOI: 10.4103/ijmy.ijmy_139_24

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