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Article

Potential of nanopore sequencing for tuberculosis diagnosis and drug resistance detection.

BMC infectious diseases - 28 Dec 2024

Ren Fei, Ma JinBao, Dang LiYun, Li AiFang, Zhao GuoLian, Qi Yun, Xu You, Yang Han, Li JianYing

Abstract excerpt

OBJECTIVES: This study evaluates the effectiveness of nanopore sequencing for accurate detection of Mycobacterium tuberculosis pathogens and drug resistance mutations in clinical specimens. METHODS: A retrospective analysis of 2,421 specimens from suspected tuberculosis patients admitted to Xi'an Chest Hospital from 2022 to 2023 was conducted, with 131 specimens undergoing via real-time, fluorescence-based...

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Drug Resistance, Bacterial
Mutation
Mycobacterium research and diagnosis
Mycobacterium tuberculosis
Nanopore Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sensitivity and Specificity

Tuberculosis Research and Epidemiology

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PMID: 39731145
DOI: 10.1186/s12879-024-10378-0
PMCID: PMC11681766

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