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The Molecular Classification of Pheochromocytomas and Paragangliomas: Discovering the Genomic and Immune Landscape of Metastatic Disease

28 Oct 2024

Abstract excerpt

Pheochromocytomas (PCCs) and paragangliomas (PGLs, together PPGLs) are the most hereditary tumors known. PPGLs were considered benign, but the fourth edition of the World Health Organisation (WHO) classification redefined all PPGLs as malignant neoplasms with variable metastatic potential. The metastatic rate differs based on histopathology, genetic background, size, and location of the tumor. The challenge in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39466488
DOI: 10.1007/s12022-024-09830-3

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