Article
New Perspectives on Pheochromocytoma and Paraganglioma: Toward a Molecular Classification.
Endocrine reviews - 1 Dec 2017
Crona Joakim, Taïeb David, Pacak Karel
Abstract excerpt
A molecular biology-based taxonomy has been proposed for pheochromocytoma and paraganglioma (PPGL). Data from the Cancer Genome Atlas revealed clinically relevant prognostic and predictive biomarkers and stratified PPGLs into three main clusters. Each subgroup has a distinct molecular-biochemical-imaging signature. Concurrently, new methods for biochemical analysis, functional imaging, and medical therapies have...
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