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Article

Genetics of pheochromocytoma and paraganglioma.

Current opinion in endocrinology, diabetes, and obesity - 1 Jun 2021

Wachtel Heather, Fishbein Lauren

Abstract excerpt

PURPOSE OF REVIEW: This review summarizes our current understanding of germline and somatic genetics and genomics of pheochromocytomas and paragangliomas (PCC/PGL), describes existing knowledge gaps, and discusses future research directions. RECENT FINDINGS: Germline pathogenic variants (PVs) are found in up to 40% of those with PCC/PGL. Tumors with germline PVs are broadly categorized as Cluster 1...

Topics

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Adrenal Gland Neoplasms
EPAS1 gene
FH gene
Genetic Predisposition to Disease
Mutation
Paraganglioma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pheochromocytoma

Signal Transduction

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Identifiers

PMID: 33764930
DOI: 10.1097/MED.0000000000000634

Genes

EPAS1
NF1
RET
VHL
ATRX
CSDE1
FH
HRAS
MAML3
MAX
TERT
TMEM127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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