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Article

HBV DNA integration and somatic mutations in HCC patients with HBV-HCV dual infection reveals profiles intermediate between HBV- and HCV-related HCC.

Journal of biomedical science - 2 Jan 2025

Li Chiao-Ling, Hsu Chia-Lang, Lin You-Yu, Ho Ming-Chih, Hu Rey-Heng, Tzeng Sheng-Tai, Wang Ya-Chun, Tanaka Yasuhito, Chen Pei-Jer, Yeh Shiou-Hwei

Abstract excerpt

BACKGROUND: In regions with a high prevalence of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, coinfected patients face a heightened risk of developing hepatocellular carcinoma (HCC), termed HBV/HCV-related HCC (HBCV-HCC). We aimed to investigate the contribution of preexisting chronic hepatitis B (CHB) and subsequent chronic hepatitis C (CHC) to the development of HBCV-HCC. METHODS: We...

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Identifiers

PMID: 39743539
DOI: 10.1186/s12929-024-01094-7
PMCID: PMC11694426

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