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Article

Distinct Patterns of HBV Integration and TERT Alterations between in Tumor and Non-Tumor Tissue in Patients with Hepatocellular Carcinoma.

International journal of molecular sciences - 30 Jun 2021

Jang Jeong-Won, Kim Hye-Seon, Kim Jin-Seoub, Lee Soon-Kyu, Han Ji-Won, Sung Pil-Soo, Bae Si-Hyun, Choi Jong-Young, Yoon Seung-Kew, Han Dong-Jin, Kim Tae-Min, Roberts Lewis R

Abstract excerpt

Although hepatitis B virus (HBV) integration into the cellular genome is well known in HCC (hepatocellular carcinoma) patients, its biological role still remains uncertain. This study investigated the patterns of HBV integration and correlated them with TERT (telomerase reverse transcriptase) alterations in paired tumor and non-tumor tissues. Compared to those in non-tumors, tumoral integrations occurred less...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34209079
DOI: 10.3390/ijms22137056
PMCID: PMC8268258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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