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Impact of Aberrant β-Catenin Pathway on Cholangiocarcinoma Heterogeneity

12 Apr 2023

Abstract excerpt

The poor prognosis of most cases of advanced cholangiocarcinoma (CCA) constitutes a severe problem in modern oncology, which is aggravated by the fact that the incidence of this liver cancer is increasing worldwide and is often diagnosed late, when surgical removal is not feasible. The difficulty of dealing with this deadly tumor is augmented by the heterogeneity of CCA subtypes and the complexity of mechanisms...

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PMID: 37190050
DOI: 10.3390/cells12081141

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