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Article

Mouse testicular macrophages can independently produce testosterone and are regulated by Cebpb

9 Sept 2024

Abstract excerpt

BACKGROUND: Testicular macrophages (TM) have long been recognized for their role in immune response within the testicular environment. However, their involvement in steroid hormone synthesis, particularly testosterone, has not been fully elucidated. This study aims to explore the capability of TM to synthesize and secrete testosterone de novo and to investigate the regulatory mechanisms involved. RESULTS:...

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PMID: 39252136
DOI: 10.1186/s40659-024-00544-8

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