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Article

New Insights into Testosterone Biosynthesis: Novel Observations from HSD17B3 Deficient Mice.

International journal of molecular sciences - 8 Dec 2022

Lawrence Ben M, O'Donnell Liza, Smith Lee B, Rebourcet Diane

Abstract excerpt

Androgens such as testosterone and dihydrotestosterone (DHT) are essential for male sexual development, masculinisation, and fertility. Testosterone is produced via the canonical androgen production pathway and is essential for normal masculinisation and testis function. Disruption to androgen production can result in disorders of sexual development (DSD). In the canonical pathway, 17β-hydroxysteroid...

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Identifiers

PMID: 36555196
DOI: 10.3390/ijms232415555
PMCID: PMC9779265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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