Article
Characterization of the Micro-Environment of the Testis that Shapes the Phenotype and Function of Testicular Macrophages.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2017
Wang Ming, Fijak Monika, Hossain Hamid, Markmann Melanie, Nüsing Rolf M, Lochnit Günter, Hartmann Michaela F, Wudy Stefan A, Zhang Lizong, Gu Huanpeng, Konrad Lutz, Chakraborty Trinad, Meinhardt Andreas, Bhushan Sudhanshu
Abstract excerpt
Macrophages are important in the activation of innate immune responses and in a tissue-specific manner in the maintenance of organ homeostasis. Testicular macrophages (TM), which reside in the testicular interstitial space, comprise the largest leukocyte population in the testes and are assumed to play a relevant function in maintaining testicular immune privilege. Numerous studies have indicated that the...
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