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Article

Macrophages Contribute to the Spermatogonial Niche in the Adult Testis

1 Aug 2015

Abstract excerpt

The testis produces sperm throughout the male reproductive lifespan by balancing self-renewal and differentiation of spermatogonial stem cells (SSCs). Part of the SSC niche is thought to lie outside the seminiferous tubules of the testis; however, specific interstitial components of the niche that regulate spermatogonial divisions and differentiation remain undefined. We identified distinct populations of...

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PMID: 26257171
DOI: 10.1016/j.celrep.2015.07.015

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