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Improving Reliability of Immunological Assays by Defining Minimal Criteria for Cell Fitness

1 Sept 2024

Abstract excerpt

Human PBMC-based assays are often used as biomarkers for the diagnosis and prognosis of disease, as well as for the prediction and tracking of response to biological therapeutics. However, the development and use of PBMC-based biomarker assays is often limited by poor reproducibility. Complex immunological assays can be further complicated by variation in cell handling before analysis, especially when using...

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PMID: 39248805
DOI: 10.4049/immunohorizons.2300095

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