Article
Effects of long-term cryopreservation of PBMC on recovery of B cell subpopulations.
Journal of immunological methods - 1 Aug 2021
Ticha Olga, Moos Lukas, Bekeredjian-Ding Isabelle
Abstract excerpt
Cryopreservation of human peripheral blood mononuclear cells (PBMC) is used in many clinical and research applications to avoid direct and on-site analysis of samples. Storage of PBMC further allows prequalification of donor cells for routine laboratory methods involving the evaluation of immune responses. Previous studies reported changes in cellular composition and phenotype of PBMC following the freezing...
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