Phenotypic and functional comparisons between cryopreserved and freshly isolated peripheral blood mononuclear cells with or without red blood cell lysate (ACK) treatment with special focus on regulatory T cells.

Abstract excerpt

Adaptive transfer of autologous regulatory T cells (Treg), or ex vivo-generated immunomodulatory cells, has shown promise in reducing/withdrawing immunosuppression after organ transplantation. The effect of cryopreserving such cells is still unclear. This study aims to evaluate the effects of cryopreservation on the immunomodulatory functions of peripheral blood mononuclear cells (PBMCs) with or without...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Survival
• Share to Cryopreservation