Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circulating Tumor DNA in Patients with Desmoid Fibromatosis during Active Surveillance.

Annals of surgical oncology - 1 Dec 2024

Bergamaschi Laura, Zorza Marta, Rini Francesca, Perrone Federica, Rivoltini Licia, Gronchi Alessandro, Pasquali Sandro, Zaffaroni Nadia, Vallacchi Viviana, Colombo Chiara

Abstract excerpt

BACKGROUND: Sporadic desmoid fibromatosis (DF) is a rare locally aggressive tumor characterized by mutation in exon 3 of CTNNB1 (T41A, S45F, and S45P). Standard of care is active surveillance (AS), but 30% require treatment. DF clinical course is unpredictable and identification of prognostic markers is needed to tailor strategy. In this prospective study, we investigated the consistency between mutation detected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Circulating Tumor DNA

Share to Desmoid Tumors

Share to Follow-Up Studies

Share to Prognosis

Share to Young Adult

Source

Identifiers

PMID: 39244517
DOI: 10.1245/s10434-024-16147-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circulating Tumor DNA in Patients with Desmoid Fibromatosis during Active Surveillance.PMID 39244517Read ↗

Droplet Digital PCR (ddPCR) as a Novel Technology in Detecting CTNNB1 Mutations in Desmoid Fibromatosis.Semantic proximity Read ↗

Desmoid fibromatosis: is the current picture changing?Semantic proximity Read ↗

Next-generation sequencing is highly sensitive for the detection of beta-catenin mutations in desmoid-type fibromatoses.Semantic proximity Read ↗

Clinical results of active surveillance for extra-abdominal desmoid-type fibromatosis.Semantic proximity Read ↗

A Nationwide Prospective Clinical Trial on Active Surveillance in Patients With Non-intraabdominal Desmoid-type Fibromatosis: The GRAFITI Trial.Semantic proximity Read ↗

Lower Rate of CTNNB1 Mutations and Higher Rate of APC Mutations in Desmoid Fibromatosis of the Breast: A Series of 134 Tumors.Semantic proximity Read ↗

Novel pathogenic alterations in pediatric and adult desmoid-type fibromatosis – A systematic analysis of 204 casesSemantic proximity Read ↗

Desmoid tumor: a disease opportune for molecular insights.Semantic proximity Read ↗

The Prognostic Role of β-Catenin Mutations in Desmoid-type Fibromatosis Undergoing Resection Only: A Meta-analysis of Individual Patient Data.Semantic proximity Read ↗

Novel intra-genic large deletions of CTNNB1 gene identified in WT desmoid-type fibromatosis.Semantic proximity Read ↗

CTNNB1 Mutational analysis enhances diagnostic precision in β-catenin-negative desmoid fibromatosis: a clinicopathological and molecular study.Semantic proximity Read ↗

CTNNB1 mutation analysis is a useful tool for the diagnosis of desmoid tumors: a study of 260 desmoid tumors and 191 potential morphologic mimics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.