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A Nationwide Prospective Clinical Trial on Active Surveillance in Patients With Non-intraabdominal Desmoid-type Fibromatosis: The GRAFITI Trial.

Annals of surgery - 1 Apr 2023

Schut Anne-Rose W, Timbergen Milea J M, van Broekhoven Danique L M, van Dalen Thijs, van Houdt Winan J, Bonenkamp Johannes J, Sleijfer Stefan, Grunhagen Dirk J, Verhoef Cornelis

Abstract excerpt

OBJECTIVE: To assess tumor behavior and the efficacy of active surveillance (AS) in patients with desmoid-type fibromatosis (DTF). SUMMARY OF BACKGROUND DATA: AS is recommended as initial management for DTF patients. Prospective data regarding the results of AS are lacking. METHODS: In this multicenter prospective cohort study (NTR4714), adult patients with non-intraabdominal DTF were followed during an initial...

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PMID: 35166264
DOI: 10.1097/SLA.0000000000005415
PMCID: PMC9994811

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